Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal hydantoin syndrome, also called fetal dilantin syndrome is a group of defects caused to the developing fetus by exposure to the teratogenic effects of phenytoin or carbamazepine. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy. It may also be called congenital hydantoin syndrome, Fetal Hydantoin Syndrome, Dilantin Embryopathy, or Phenytoin Embryopathy. About one third of children whose mothers are taking this drug during pregnancy typically have intrauterine growth restriction with microcephaly and develop minor dysmorphic craniofacial features and limb defects including hypoplastic nails and distal phalanges (birth defects). A smaller population will have growth problems and developmental delay, or mental retardation. Rare side effects include methemoglobinemia.

Fetal Hydantoin Syndrome 

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome

Fetal Hydantoin Syndrome