Birth Defects List

Birth Defects List

Thalidomide ( /θəˈlɪdəmaɪd/) is a sedative drug introduced in the late 1950s that was used to treat morning sickness and to aid sleep. It was sold from 1957 until 1961, when it was withdrawn after being found to be a teratogen - a cause of birth defects. Modern uses of thalidomide (trademarked as Thalomid, according to FDA Orange Book) include treating multiple myeloma in combination with dexamethasone,  and erythema nodosum leprosum, with strict controls on its use to prevent birth defects. Research is ongoing in its use to treat other cancers and autoimmune conditions, although its use is controversial; the thalidomide tragedy led to much stricter testing being introduced for drug and pesticide licensing. A congenital disorder, or congenital disease, is a condition existing at birth and often before birth, or that develops during the first month of life (neonatal disease), regardless of causation. Of these diseases, those characterized by structural deformities are termed "congenital anomalies" and involve defects in or damage to a developing fetus. A congenital disorder may be the result of genetic abnormalities, the intrauterine (uterus) environment, errors of morphogenesis, infection, or a chromosomal abnormality. 

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List

Birth Defects List