Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic generalized epilepsy (IGE) is a group of epileptic disorders that are believed to have a strong underlying genetic basis. Patients with an IGE subtype are typically otherwise normal and have no anatomical brain abnormalities. Patients also often have a family history of epilepsy and seem to have a genetically predisposed risk of attack. IGE tends to manifest itself between early childhood and adolescence although it can be eventually diagnosed later. The genetic cause of some IGE types is known, though inheritance does not always follow a simple monogenic mechanism. Generalized epilepsy with febrile seizures plus (GEFS+) is an umbrella for many other syndromes that share causative genes. Patients experience febrile seizures early in childhood and grow to experience other types of seizures later in life. Known causative genes for GEFS+ are the sodium channel α subunit genes SCN1A and SCN2A and the β subunit gene SCN1B. Mutations in the GABAA receptor γ subunit GABRG1 are also causative for this disorder.

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy

Idiopathic Epilepsy