A blister is a small pocket of fluid within the upper layers of the skin, typically caused by forceful rubbing (friction), burning, freezing, chemical exposure or infection. Most blisters are filled with a clear fluid called serum or plasma.[1] However, blisters can be filled with blood (known as blood blisters) or with pus (if they become infected). The word "blister" entered English in the 14th century. It came from the Middle Dutch "bluyster", and was a modification of the Old French "blostre" which meant a leprous nodule—a rise in the skin due to leprosy. Feet are an important component for a successful hike and sore feet are a great way to ruin an otherwise great experience. There’s nothing worse than feeling the slow formation of a blister and the jolts of pain that surge from you foot with each step. Foot blisters will slow the step of the most determined hiker. Friction blisters are caused by excess shear stress between the surface of the skin and the body. The strata (a thin layer) of skin around the Stratum lucidum is most susceptible to shear. As the Stratum lucidum tears away from the connecting tissues below, plasma from the cells diffuses (spreads freely) out. This plasma solution helps new cells divide and grow into new connective tissues and epidermal layers.
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